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Social environmental risk factors for transition to psychosis in an Ultra-High Risk population.

Identifieur interne : 001B36 ( Main/Exploration ); précédent : 001B35; suivant : 001B37

Social environmental risk factors for transition to psychosis in an Ultra-High Risk population.

Auteurs : Brian O'Donoghue [Royaume-Uni] ; Barnaby Nelson [Australie] ; Hok Pan Yuen [Australie] ; Abbie Lane [Irlande (pays)] ; Stephen Wood [Australie] ; Andrew Thompson [Australie] ; Ashleigh Lin [Australie] ; Patrick Mcgorry [Australie] ; Alison R. Yung [Royaume-Uni]

Source :

RBID : pubmed:25439392

Descripteurs français

English descriptors

Abstract

OBJECTIVE

Despite social environmental factors such as deprivation, urbanicity, migration and adversity being established risk factors for psychotic disorders, there is a paucity of knowledge on the influence of social environmental risk factors in the UHR population. Firstly, we aimed to investigate the association between social deprivation and risk of transition and secondly, we aimed to investigate the association between migration status and the risk of transition.

METHOD

UHR individuals at the Personal Assessment and Crisis Evaluation (PACE) service in Melbourne were included. Social deprivation as assessed according to postal code area of residence was obtained from census data and Cox regression analysis was used to calculate hazard ratios.

RESULTS

A total of 219 UHR individuals were included and over the median follow-up time of 4.8years, 32 individuals (14.6%) were known to have transitioned to a psychotic disorder. 8.8% of UHR individuals were first generation migrants and 41.9% were second generation migrants. The level of social deprivation was not associated with the risk of transition (p=0.83). Similarly, first or second generation migrants did not have an increased risk of transition to psychosis (p=0.84).

CONCLUSIONS

Despite being established risk factors for psychotic disorders, social deprivation and migrant status have not been found to increase the risk of transition in a UHR population.


DOI: 10.1016/j.schres.2014.10.050
PubMed: 25439392


Affiliations:


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Le document en format XML

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<term>Male (MeSH)</term>
<term>Prodromal Symptoms (MeSH)</term>
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<p>
<b>OBJECTIVE</b>
</p>
<p>Despite social environmental factors such as deprivation, urbanicity, migration and adversity being established risk factors for psychotic disorders, there is a paucity of knowledge on the influence of social environmental risk factors in the UHR population. Firstly, we aimed to investigate the association between social deprivation and risk of transition and secondly, we aimed to investigate the association between migration status and the risk of transition.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHOD</b>
</p>
<p>UHR individuals at the Personal Assessment and Crisis Evaluation (PACE) service in Melbourne were included. Social deprivation as assessed according to postal code area of residence was obtained from census data and Cox regression analysis was used to calculate hazard ratios.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>A total of 219 UHR individuals were included and over the median follow-up time of 4.8years, 32 individuals (14.6%) were known to have transitioned to a psychotic disorder. 8.8% of UHR individuals were first generation migrants and 41.9% were second generation migrants. The level of social deprivation was not associated with the risk of transition (p=0.83). Similarly, first or second generation migrants did not have an increased risk of transition to psychosis (p=0.84).</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSIONS</b>
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<p>Despite being established risk factors for psychotic disorders, social deprivation and migrant status have not been found to increase the risk of transition in a UHR population.</p>
</div>
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<Year>2015</Year>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Despite social environmental factors such as deprivation, urbanicity, migration and adversity being established risk factors for psychotic disorders, there is a paucity of knowledge on the influence of social environmental risk factors in the UHR population. Firstly, we aimed to investigate the association between social deprivation and risk of transition and secondly, we aimed to investigate the association between migration status and the risk of transition.</AbstractText>
<AbstractText Label="METHOD" NlmCategory="METHODS">UHR individuals at the Personal Assessment and Crisis Evaluation (PACE) service in Melbourne were included. Social deprivation as assessed according to postal code area of residence was obtained from census data and Cox regression analysis was used to calculate hazard ratios.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 219 UHR individuals were included and over the median follow-up time of 4.8years, 32 individuals (14.6%) were known to have transitioned to a psychotic disorder. 8.8% of UHR individuals were first generation migrants and 41.9% were second generation migrants. The level of social deprivation was not associated with the risk of transition (p=0.83). Similarly, first or second generation migrants did not have an increased risk of transition to psychosis (p=0.84).</AbstractText>
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<CopyrightInformation>Copyright © 2014 Elsevier B.V. All rights reserved.</CopyrightInformation>
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<ForeName>Ashleigh</ForeName>
<Initials>A</Initials>
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<Affiliation>Telethon Kids Institute, The University of Western Australia, Australia.</Affiliation>
</AffiliationInfo>
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<LastName>McGorry</LastName>
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<Affiliation>Orygen Youth Health Research Centre, 35 Poplar rd, Parkville, Victoria, Australia; University of Melbourne, Parkville, Victoria, Australia.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Yung</LastName>
<ForeName>Alison R</ForeName>
<Initials>AR</Initials>
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<Affiliation>Orygen Youth Health Research Centre, 35 Poplar rd, Parkville, Victoria, Australia; Institute of Brain, Behaviour and Mental Health, University of Manchester, Manchester, UK.</Affiliation>
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<Year>2014</Year>
<Month>11</Month>
<Day>28</Day>
</ArticleDate>
</Article>
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<Country>Netherlands</Country>
<MedlineTA>Schizophr Res</MedlineTA>
<NlmUniqueID>8804207</NlmUniqueID>
<ISSNLinking>0920-9964</ISSNLinking>
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<CitationSubset>IM</CitationSubset>
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<DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<DescriptorName UI="D011569" MajorTopicYN="N">Psychiatric Status Rating Scales</DescriptorName>
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<DescriptorName UI="D011618" MajorTopicYN="N">Psychotic Disorders</DescriptorName>
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<DescriptorName UI="D012931" MajorTopicYN="Y">Social Environment</DescriptorName>
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<DescriptorName UI="D012934" MajorTopicYN="N">Social Isolation</DescriptorName>
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<DescriptorName UI="D014171" MajorTopicYN="N">Transients and Migrants</DescriptorName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
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<MeshHeading>
<DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
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<Keyword MajorTopicYN="N">Migrants</Keyword>
<Keyword MajorTopicYN="N">Psychosis</Keyword>
<Keyword MajorTopicYN="N">Social deprivation</Keyword>
<Keyword MajorTopicYN="N">Ultra-High Risk for psychosis</Keyword>
</KeywordList>
</MedlineCitation>
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<Year>2014</Year>
<Month>06</Month>
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<PubMedPubDate PubStatus="revised">
<Year>2014</Year>
<Month>09</Month>
<Day>23</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted">
<Year>2014</Year>
<Month>10</Month>
<Day>28</Day>
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<Month>12</Month>
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<Hour>6</Hour>
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<PublicationStatus>ppublish</PublicationStatus>
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<ArticleId IdType="pubmed">25439392</ArticleId>
<ArticleId IdType="pii">S0920-9964(14)00647-1</ArticleId>
<ArticleId IdType="doi">10.1016/j.schres.2014.10.050</ArticleId>
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</PubmedData>
</pubmed>
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<list>
<country>
<li>Australie</li>
<li>Irlande (pays)</li>
<li>Royaume-Uni</li>
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<region>
<li>Angleterre</li>
<li>Grand Manchester</li>
<li>Leinster</li>
<li>Midlands de l'Ouest</li>
<li>Victoria (État)</li>
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<settlement>
<li>Birmingham</li>
<li>Dublin</li>
<li>Manchester</li>
<li>Melbourne</li>
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<orgName>
<li>University College Dublin</li>
<li>Université de Birmingham</li>
<li>Université de Manchester</li>
<li>Université de Melbourne</li>
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<name sortKey="O Donoghue, Brian" sort="O Donoghue, Brian" uniqKey="O Donoghue B" first="Brian" last="O'Donoghue">Brian O'Donoghue</name>
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<name sortKey="Yung, Alison R" sort="Yung, Alison R" uniqKey="Yung A" first="Alison R" last="Yung">Alison R. Yung</name>
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<name sortKey="Nelson, Barnaby" sort="Nelson, Barnaby" uniqKey="Nelson B" first="Barnaby" last="Nelson">Barnaby Nelson</name>
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<name sortKey="Lin, Ashleigh" sort="Lin, Ashleigh" uniqKey="Lin A" first="Ashleigh" last="Lin">Ashleigh Lin</name>
<name sortKey="Mcgorry, Patrick" sort="Mcgorry, Patrick" uniqKey="Mcgorry P" first="Patrick" last="Mcgorry">Patrick Mcgorry</name>
<name sortKey="Thompson, Andrew" sort="Thompson, Andrew" uniqKey="Thompson A" first="Andrew" last="Thompson">Andrew Thompson</name>
<name sortKey="Wood, Stephen" sort="Wood, Stephen" uniqKey="Wood S" first="Stephen" last="Wood">Stephen Wood</name>
<name sortKey="Yuen, Hok Pan" sort="Yuen, Hok Pan" uniqKey="Yuen H" first="Hok Pan" last="Yuen">Hok Pan Yuen</name>
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<country name="Irlande (pays)">
<region name="Leinster">
<name sortKey="Lane, Abbie" sort="Lane, Abbie" uniqKey="Lane A" first="Abbie" last="Lane">Abbie Lane</name>
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</record>

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